Ted Standiford, MD
Dr. Standiford is a scientific advisor to Asalyxa Bio. He graduated from the Wayne State University School of Medicine in 1984, where he was selected to the Alpha Omega Alpha Honor Society. After residency in internal medicine at the University of Minnesota, Dr. Standiford came to Ann Arbor for a fellowship in Pulmonary and Critical Care Medicine. He performed his research fellowship in the laboratories of Robert Strieter, M.D. and Steven Kunkel, Ph.D., where he investigated the biology of chemokines in inflammatory lung disease. After fellowship, he joined the faculty in 1991 as an assistant professor and rose through the ranks to be named full professor in 2000. He was appointed as interim division chief of the Division of Pulmonary and Critical Care Medicine in 2011; he was named division chief in 2014. He was named the Henry Sewall Professor of Medicine in 2015.
Dr. Standiford is a recognized expert in basic and translational research exploring immune responses in the lung. He performed some of the landmark studies to identify the cellular sources and biological activities of chemokines expressed in the lung, and has defined the role of specific cells, cytokines, and antimicrobial peptides in the lung’s innate immunity against microbial respiratory pathogens. His research has identified the importance of pathogen recognition receptors – including both toll-like receptors and Nod-like receptors – in lung mucosal immunity, and has defined how downstream pathogen recognition receptor signaling is regulated by both immunological and epigenetic mechanisms. His laboratory has uncovered basic mechanisms of experimental lung injury in response to infectious and non-infectious insults. In human studies, he has investigated mechanisms of lung injury in sepsis and acute respiratory distress syndrome (ARDS), and performed human trials to assess the effect of growth factor administration on outcome of patients with ARDS. His bibliography lists over 270 peer-reviewed publications, multiple topic reviews, and book chapters. He has published his research in some of the highest visibility journals, including the Journal of Clinical Investigation, the Journal of Immunology, the American Journal of Respiratory and Critical Care Medicine, and the New England Journal of Medicine.
Dr. Standiford’s research has received robust and continuous NIH grant funding. He served as program director of two large multi-investigator project grants here at Michigan: the Specialized Center of Research in Acute Lung Injury (2000-2002) and the Specialized Center of Clinically-Oriented Research in Acute Lung Injury (2003-2009). He directs the Division’s NIH/NHLBI T32 Postgraduate Research Training Grant in Lung Diseases, one of the largest of its kind in the country. He served as a standing member on multiple NIH and Foundation study sections. He is an elected member of the American Society for Clinical Investigation (ASCI) and the Association of American Physicians (AAP).
Dr. Standiford has been the recipient of major departmental and national awards for research, teaching, and administrative contributions. These awards include the Jerome Conn Excellence in Biomedical Research Award, the House Officer Teaching Award, and the Chairman’s Award for Outstanding Service to the Department. He received the Recognition Award for Scientific Accomplishments from the American Thoracic Society in 2019.